Fig. 3a, b.

Rotenone influences the P2X7 receptor current densities, which are related to cell age or LPS pretreatment. a After 24 h recovery, astrocytes were treated with rotenone for 24 or 48 h (groups 24hours and 48hours) before the currents were tested by 100 μM BzATP. After 48 h recovery, astrocytes were treated with 2 and 20 nM rotenone for 24 h (group 24hours′), and the current densities did not increase. b After 24 h recovery, astrocytes were treated with rotenone and 10 μg/ml LPS for 24 or 48 h (groups 24hours and 48hours) before the currents were tested by 100 μM BzATP