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. 2011 Mar 9;286(17):15032–15042. doi: 10.1074/jbc.M110.199752

FIGURE 9.

FIGURE 9.

Fraction of interacting donors at different Pi content for the different NaPi/PDZ pairs as obtained from the phasor analysis of FRET data. A significant increase of interacting donors was observed for the pair NaPi-2c/PDZK1 at low Pi concentrations (0.1%) in the medium, whereas the pair NaPi-2c/NHERF-1 was not affected. A similar increase of interacting donors was shown for the pair NaPi-2a/NHERF-1 with no changes for NaPi-2a/PDZK1. These results highlight the importance of the interaction NaPi-2c/PDZK1 in the adaptive response to low Pi concentrations.