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. Author manuscript; available in PMC: 2011 Apr 27.
Published in final edited form as: Br J Haematol. 2008 Nov 22;144(3):388–394. doi: 10.1111/j.1365-2141.2008.07461.x

Table I.

Demographic characteristics by CDD A79C genotype

AA AC CC AC+CC AA vs AC+CC
Characteristic N % N % N % N % P
Total 229 179 49 228
Age: median & range (yrs) 10.5 (0.15 – 20.9) 10.0 (0.01 – 19.8) 9.6 (0.13 – 18.4) 10.0 (0.01 – 19.8) 0.61
WBC: median & range Study 18,900 (300 – 860,000) 19,600 (1,000 – 600,000) 25,500 (1,500 – 324,000) 20,800 (1,000 – 600,000) 0.61
CCG-2941 13 6 18 10 7 14 25 11 0.06
CCG-2961 216 94 161 90 42 86 203 89
Gender
Male 130 57 96 54 25 51 121 53 0.48
Female 99 43 83 46 24 49 107 47
Race
White 129 57 142 79 41 84 183 80 <0.001
Black 33 14 5 3 1 2 6 3 <0.001
Hispanic 42 18 23 13 7 14 30 13 0.16
Asian 11 5 3 2 0 0 3 1 0.06
Other 13 6 6 3 0 0 6 3 0.16
Unknown 1 0 0 0
FAB subtype
M0 8 4 13 7 4 8 17 8 0.10
M1 32 14 35 20 4 8 39 17 0.43
M2 67 29 48 27 16 33 64 28 0.86
M4 63 28 45 25 11 22 0.54
56 25
M5 40 17 29 16 8 16 37 16 0.82
M6 7 3 2 1 1 2 3 1 0.34
M7 7 3 4 2 5 10 9 4 0.79
De novo (NOS) 5 2 3 2 0 0 3 1 0.72
Cytogenetics
Normal 32 23 24 22 10 34 34 25 0.92
t(8;21) 27 20 16 15 3 10 19 14 0.25
Abn 16 14 10 9 8 4 14 13 9 0.98
Abn 11 27 20 25 23 5 17 30 22 0.79
t(6;9) 1 1 4 4 0 0 4 3 0.37
−7/7- 4 3 4 4 0 0 4 3 1.000
−5/5- 2 2 1 1 1 3 2 1 1.000
+8 7 5 9 8 2 7 11 8 0.47
+21 0 0 2 2 0 0 2 1 0.50
Pseudodiploid 16 12 9 8 4 14 13 9 0.68
Hyperdiploid 5 4 3 3 0 0 3 2 0.50
Hypodiploid 2 2 3 3 0 0 3 2 1.000
Unknown 92 40 70 39 20 41 90 39
Response at end of first course
Remission 196 87 147 87 45 92 192 88 0.87
Failure 19 8 10 6 2 4 12 6 0.31
Death 10 4 12 7 2 4 14 6 0.48
Inevaluable 4 10 0 10