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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Expert Opin Drug Discov. 2011 Feb;6(2):185–193. doi: 10.1517/17460441.2011.547468

Figure 1. A saturating concentration of a theoretical full agonist elicits a greater response than a saturating concentration of a theoretical partial agonist.

Figure 1

(A) A theoretical full agonist versus a relatively effective theoretical partial agonist. The activity of these ligands resembles the activity of AREG (full agonist) and EGF (partial agonist). (B) A theoretical full agonist versus a relatively ineffective theoretical partial agonist. The activity of these ligands resembles the activity of wild-type NRG2β (full agonist) and NRG2β/Q43L (partial agonist).