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. Author manuscript; available in PMC: 2012 Apr 28.
Published in final edited form as: J Med Chem. 2011 Mar 21;54(8):2891–2901. doi: 10.1021/jm101642g

Figure 6.

Figure 6

(A) Mass spectra for the control (inset) and 6-cyano-2′-deoxy-2′-fluoro-UMP (35) treated ODCases. (B) The biochemical transformation of 6-cyano- and 6-cyano-2′-deoxy-2′-fluoro-UMP derivatives by ODCase. In the former case, a hydrolytic process was observed, while in the latter case a covalent complex was observed in the active site of ODCase.