Table 5.
Ten-year cardiovascular riska (%) estimated with the Framingham equation by gender- and method-specific quintiles of measured or estimated GFR
| GFR Method | Quintile 1 (95% CI) | Quintile 2 (95% CI) | Quintile 3 (95% CI) | Quintile 4 (95% CI) | Quintile 5 (95% CI) | P for Linear Trend | |
|---|---|---|---|---|---|---|---|
| Measured GFR | Female | 5.6 (5.1 to 6.1) | 5.5 (5.0 to 6.0) | 5.5 (5.0 to 6.1) | 6.1 (5.6 to 6.6) | 6.2 (5.7 to 6.8) | 0.02 |
| Male | 21.7 (19.6 to 23.9) | 19.7 (17.5 to 21.8) | 20.1 (18.0 to 22.3) | 20.4 (18.2 to 22.5) | 21.4 (19.2 to 23.5) | 1.00 | |
| MDRD equation | Female | 5.6 (5.1 to 6.1) | 5.5 (5.0 to 6.0) | 5.6 (5.1 to 6.1) | 5.9 (5.4 to 6.5) | 6.3 (5.8 to 6.8) | 0.02 |
| Male | 20.6 (18.4 to 22.8) | 20.5 (18.3 to 22.7) | 19.5 (17.4 to 21.7) | 21.5 (19.3 to 23.6) | 21.2 (19.1 to 23.4) | 0.52 | |
| CKD-EPI equation | Female | 5.5 (5.0 to 6.0) | 5.7 (5.2 to 6.3) | 5.3 (4.8 to 5.8) | 5.9 (5.4 to 6.4) | 6.5 (6.0 to 7.1) | 0.01 |
| Male | 21.0 (18.8 to 23.1) | 19.3 (17.1 to 21.5) | 21.3 (19.1 to 23.4) | 20.3 (18.2 to 22.5) | 21.4 (19.2 to 23.7) | 0.58 | |
| Rule's cystatin C equation | Female | 6.7 (6.1 to 7.2) | 6.2 (5.7 to 6.7) | 5.4 (4.9 to 5.9) | 5.7 (5.3 to 6.2) | 5.0 (4.5 to 5.5) | <0.0001 |
| Male | 25.4 (23.3 to 27.6) | 22.3 (20.2 to 24.4) | 21.8 (19.6 to 24.0) | 18.5 (16.5 to 20.5) | 16.0 (13.9 to 18.1) | <0.0001 |
Quintile 1 is the lowest, and quintile 5 the highest. CI, confidence interval.
aThere were no diabetics included in the study population.