Table 2.

Hazard ratios of the composite outcome of death or allograft loss according to natural log-transformed FGF23 (per 1 SD increase) and ascending tertiles of FGF23

	Natural log FGF23		FGF23 Tertiles
	per 1 SD	P	1	2	3	Pa
All patients, n = 984
crude	1.94	<0.001	Reference	1.96	6.49	<0.001
	1.77, 2.13			1.19, 3.25	4.15, 10.1
eGFR	1.61	<0.001	Reference	1.40	3.04	<0.001
	1.43, 1.82			0.84, 2.33	1.89, 4.9
eGFR, age, gender	1.62	<0.001	Reference	1.34	2.84	<0.001
	1.43, 1.84			0.80, 2.24	1.76, 4.57
full model	1.46	<0.001	Reference	1.39	2.27	<0.001
	1.28, 1.68			0.83, 2.33	1.38, 3.72
full model + phosphate	1.42	<0.001	Reference	1.42	2.23	0.001
	1.23, 1.62			0.85, 2.39	1.35, 3.67
full model + logPTH	1.44	<0.001	Reference	1.39	2.23	0.001
	1.25, 1.65			0.83, 2.33	1.35, 3.66
Restricted to patients with eGFR 30 to 90 ml/min per 1.73 m2, n = 765
crude	1.63	<0.001	Reference	1.75	3.96	<0.001
	1.37, 1.94			0.99, 3.12	2.32, 6.77
eGFR	1.57	<0.001	Reference	1.55	2.92	<0.001
	1.29, 1.92			0.87, 2.77	1.67, 5.05
eGFR, age, gender	1.55	<0.001	Reference	1.51	2.61	<0.001
	1.26, 1.90			0.85, 2.70	1.50, 4.54
full model	1.43	0.002	Reference	1.57	2.24	0.005
	1.14, 1.78			0.87, 2.80	1.27, 3.94
full model + phosphate	1.45	0.001	Reference	1.57	2.29	0.004
	1.17, 1.81			0.88, 2.81	1.30, 4.03
full model + logPTH	1.42	0.003	Reference	1.54	2.18	0.007
	1.13, 1.77			0.86, 2.76	1.23, 3.85

Full model is adjusted for eGFR, age, gender, systolic BP, body mass index, albumin, calcium, Charlson score, and the duration after transplant at the time of enrollment.

^aP for linear trend.