Table 3.
Hazard ratio (95% CI) of the composite outcome of death or allograft loss according to 1 SD increase in natural log-transformed FGF23
| Phosphate Tertile 1 (<2.9 mg/dl) | Phosphate Tertile 2 (2.0 to 3.5 mg/dl) | Phosphate Tertile 3 (>3.5 mg/dl) | |
|---|---|---|---|
| Crude | 1.95 (1.34, 2.78) | 1.85 (1.45, 2.35) | 1.76 (1.57, 1.98) |
| P < 0.001 | P < 0.001 | P < 0.001 | |
| eGFR-adjusted | 1.78 (1.21, 2.59) | 1.69 (1.30, 2.20) | 1.40 (1.19, 1.65) |
| P = 0.003 | P < 0.001 | P < 0.001 | |
| Fully-adjusted | 1.67 (1.13, 2.47) | 1.52 (1.12, 2.06) | 1.37 (1.14, 1.66) |
| P = 0.009 | P = 0.008 | P = 0.001 |
Full model is adjusted for eGFR, age, gender, systolic BP, body mass index, albumin, calcium, Charlson score, and the duration after transplant at the time of enrollment.