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. 2011 May;22(5):956–966. doi: 10.1681/ASN.2010080894

Table 6.

Hazard ratios of the composite outcome of death or allograft loss according to serum phosphate (per 1 SD increase) and ascending tertiles of phosphate

Phosphate
Phosphate Tertiles
per 1 SD P 1 2 3 Pa
All patients, n = 984
    crude 1.26 <0.001 Reference 1.06 2.87 <0.001
1.19, 1.33 0.69, 1.64 1.99, 4.13
    eGFR 1.25 <0.001 Reference 0.83 1.36 0.06
1.15, 1.36 0.54, 1.29 0.92, 2.01
    eGFR, age, gender 1.28 <0.001 Reference 0.86 1.53 0.02
1.18, 1.39 0.56, 1.33 1.02, 2.28
    full model 1.28 <0.001 Reference 0.83 1.18 0.32
1.14, 1.43 0.54, 1.29 0.78, 1.79
    full model + logPTH 1.26 <0.001 Reference 0.84 1.21 0.27
1.12, 1.42 0.54, 1.31 0.80, 1.84
    full model + logFGF23 1.23 0.002 Reference 0.84 1.09 0.57
1.08, 1.40 0.54, 1.31 0.71, 1.66
Restricted to patients with eGFR 30 to 90 ml/min per 1.73 m2, n = 765
    crude 0.95 0.73 Reference 0.97 1.18 0.54
0.74, 1.24 0.60, 1.57 0.72, 1.93
    eGFR 0.83 0.23 Reference 0.86 0.94 0.79
0.61, 1.13 0.53, 1.40 0.57, 1.55
    eGFR, age, gender 0.86 0.35 Reference 0.88 1.03 0.95
0.63, 1.18 0.54, 1.43 0.61, 1.72
    full model 0.84 0.27 Reference 0.86 0.96 0.85
0.61, 1.15 0.52, 1.41 0.57, 1.61
    full model + logPTH 0.86 0.33 Reference 0.87 1.02 0.99
0.63, 1.17 0.53, 1.42 0.60, 1.71
    full model + logFGF23 0.80 0.15 Reference 0.85 0.88 0.62
    crude 0.58, 1.08 0.52, 1.40 0.52, 1.48

Full model is adjusted for eGFR, age, gender, systolic BP, body mass index, albumin, calcium, Charlson score, and the duration after transplant at the time of enrollment.

aP for linear trend.