Table 3.
Clinical and arterial parameters changes during follow-up of the 180 studied patients
| Changes | Age- and Gender-Adjusted Slopes ± SE (unit per year) | P |
|---|---|---|
| Parameters | ||
| age (years) | — | — |
| body mass index (kg/m2) | 0.13 ± 0.04 | 0.002 |
| brachial systolic BP (mmHg) | −0.4 ± 0.5 | 0.45 |
| brachial diastolic BP (mmHg) | −0.7 ± 0.3 | 0.02 |
| brachial mean BP (mmHg) | −0.5 ± 0.3 | 0.14 |
| brachial pulse pressure (mmHg) | 0.4 ± 0.3 | 0.22 |
| heart rate (beats/min) | 0.5 ± 0.3 | 0.06 |
| Large arteries | ||
| carotid-femoral pulse wave velocity (m/s) | −0.01 ± 0.04 | 0.89 |
| augmentation index (%) | −0.8 ± 0.4 | 0.045 |
| carotid systolic BP (mmHg) | −0.5 ± 0.7 | 0.50 |
| carotid diastolic BP (mmHg) | −0.8 ± 0.3 | 0.01 |
| carotid pulse pressure (mmHg) | 0.47 ± 0.52 | 0.37 |
| carotid intima-media thickness (μm) | −22 ± 4 | <0.0001 |
| carotid wall cross-sectional area (mm2) | −0.39 ± 0.09 | <0.0001 |
| carotid external diastolic diameter (mm) | 0.039 ± 0.014 | 0.006 |
| carotid internal diastolic diameter (mm) | 0.083 ± 0.015 | <0.0001 |
| carotid wall to lumen ratio (%) | −1.1 ± 0.2 | <0.0001 |
| carotid stiffness (m/s) | 0.28 ± 0.05 | <0.0001 |
| carotid Young's elastic modulus (kPa) | 59.9 ± 9.9 | <0.0001 |
| carotid circumferential wall stress (kPa) | 2.08 ± 0.43 | <0.0001 |
| Kidney | ||
| creatinine (μmol/L) | 13 ± 3 | <0.0001 |
| measured GFR (ml/min per 1.73 m2) | −1.6 ± 0.3 | <0.0001 |
| urinary albumin/creatinine ratio (mg/mmol) | 0.30 ± 0.05 | <0.0001 |