Table 4.
Relation between circumferential wall stress and measured GFR change after adjustment on cardiovascular and chronic kidney disease progression risk factors
| Parameters (unit/year) | Slope | SE | Pa |
|---|---|---|---|
| Dependent variable | |||
| measures GFR (ml/min per 1.73 m2) | −1.34 | 0.25 | <0.0001 |
| Independent parameters | |||
| age (years at baseline) | −0.15 | 0.09 | 0.07 |
| gender (male/female) | −6.09 | 2.29 | 0.0084 |
| previous CV events (yes/no) | −7.35 | 2.41 | 0.0026 |
| circumferential wall stress (kPa) | −0.28 | 0.08 | 0.0013 |
| log UACR | −8.14 | 1.18 | <0.0001 |
| carotid pulse pressure (mmHg) | −0.00 | 0.06 | NS |
UACR, urinary albumin creatinine ratio; NS, not significant.
aLinear mixed-model regression over time, adjusted on body mass index, smoking status, diabetes, and dyslipidemia.