Table 1.
Population characteristics
| Parameters | DSA Positive (n = 40) | DSA Negative (n = 59) | P |
|---|---|---|---|
| Recipient characteristics | |||
| recipient age (years, mean ± SD) | 46 ± 12 | 48 ± 12 | NS |
| deceased donor (%) | 100% | 100% | NS |
| donor age (years, mean ± SD) | 47 ± 15 | 51 ± 14 | NS |
| cold ischemia time (hours, mean ± SD) | 27 ± 7 | 29 ± 9 | NS |
| retransplantation (%) | 22 (55%) | 4 (6.7%) | <0.001 |
| Immunology | |||
| CDC positive cross-match (n, %) | 19 (47.5%) | 0 (0%) | <0.001 |
| class I or II Peak pretransplant DSA MFImax | 7479 ± 872 | — | |
| HLA A + B mismatch (mean ± SD) | 2.1 ± 1.0 | 1.9 ± 1.1 | NS |
| HLA DR mismatch (mean ± SD) | 1.3 ± 0.7 | 0.9 ± 0.7 | NS |
| Transplant outcome | |||
| GFR at 3 months (ml/min per 1.73 m2) | 54 ± 3 | 49 ± 17 | NS |
| GFR at 1 year (ml/min per 1.73 m2) | 46 ± 3 | 49 ± 3 | NS |
| proteinuria at 3 months (g/24 h) | 0.25 ± 0.04 | 0.39 ± 0.09 | NS |
| proteinuria at 1 year (g/24 h) | 0.21 ± 0.05 | 0.43 ± 0.16 | NS |
| last SCr (μmol/dl, mean ± SD) | 214 ± 33 | 139 ± 50 | <0.001 |
| follow-up (months, mean ± SD) | 42 ± 14 | 59 ± 20 | <0.05 |
| graft loss | 2 | 2 | — |
| patient death | 0 | 0 | — |
Values expressed in mean ± SEM unless otherwise specified. NS, not significant.