Table 3.

Multivariate analysis of FH patients

		CVD Patients (%)
	Patients (n = 546)	No (n = 466)	Yes (n = 80)	OR (CI 95%)*	P	Adjusted OR** (CI 95%)	P
FVII
RR	410	350 (75.1)	60 (75.0)	1.00 (Reference)		1.00 (Reference)
RQ	127	110 (23.6)	17 (21.3)	0.89 (0.50 - 1.59)	0.70	0.76 (0.36 - 1.58)	0.46
QQ	9	6 (1.3)	3 (3.7)	2.88 (0.70 -11.84)	0.14	3.53 (0.66 - 18.92)	0.14
RQ/QQ	136	116 (24.9)	20 (25.0)	0.99 (0.58 - 1.72)	0.98	0.89 (0.45 - 1.78)	0.75
		CAD Patients (%)
	Patients (n = 546)	No (n = 471)	Yes (n = 75)	OR (CI 95%)*	P	Adjusted OR** (CI 95%)	P
FVII
RR	410	354 (75.1)	56 (74.7)	1.00 (Reference)		1.00 (Reference)
RQ	127	111 (23.5)	16 (21.3)	0.90 (0.50 - 1.63)	0.73	0.90 (0.43 - 1.87)	0.77
QQ	9	6 (1.4)	3 (4.0)	3.12 (0.76 -12.86)	0.11	3.33 (0.64 - 17.24)	0.15
RQ/QQ	136	117 (24.9)	19 (24.3)	1.02 (0.58 - 1.78)	0.96	1.05 (0.52 - 2.08)	0.90
		PAD Patients (%)
	Patients (n = 546)	No (n = 534)	Yes (n = 12)	OR (CI 95%)*	P	Adjusted OR** (CI 95%)	P
FVII
RR	410	401 (75.1)	9 (75.0)	1.00 (Reference)		1.00 (Reference)
RQ	127	125 (23.4)	2 (13.7)	0.71 (0.15 -3.34)	0.67	0.78 (0.15 - 3.84)	0.76
QQ	9	8 (1.5)	1 (8.3)	5.56 (0.63 -49.33)	0.12	5.77 (0.26 - 125.96)	0.26
RQ/QQ	136	132 (24.9)	3 (24.0)	1.00 (0.27 - 3.77)	0.99	1.03 (0.26 - 4.17)	0.96

*Crude OR obtained by univariate logistic regression analysis. **Multivariate logistic regression adjusted for sex, age, body mass index, xanthomas, arterial hypertension, smoking, diabetes mellitus, LDLc, HDLc and lipid-lowering treatment. FVII: Factor VII. FH: Heterozygous Familial Hypercholesterolemia. CVD: cardiovascular disease. CAD: coronary artery disease. PAD: peripheral artery disease.