Table 1.
Patient characteristics
| Study | Overall N = 934 |
|||||||
|---|---|---|---|---|---|---|---|---|
| CECOG GET vs FEC N = 256 |
AGO Mamma 1 N = 514 |
AGO Mamma 3 N = 164 |
||||||
| Age, years | ||||||||
| median (range) | 53.5 (29-74) | 56.0 (28-75) | 58.0 (21-76) | 56.0 (21-76) | ||||
| N | % | N | % | N | % | N | % | |
| HR status | ||||||||
| ER and/or PgR positive | 118 | 67.43 | 324 | 69.83 | 131 | 80.37 | 573 | 71.45 |
| missing | 81 | 50 | 1 | 132 | ||||
| Her2 | ||||||||
| positive | - | - | - | - | 30 | 23.08 | 30 | 23.08 |
| missing | 256 | 514 | 34 | 804 | ||||
| Nodal status at first diagnosis | ||||||||
| positive | 164 | 65.08 | 282 | 65.58 | 95 | 67.86 | 541 | 65.82 |
| missing | 4 | 84 | 24 | 112 | ||||
| ECOG PS | ||||||||
| 0 | 122 | 47.66 | 237 | 46.11 | 104 | 65.00 | 463 | 49.78 |
| 1 or 2 | 134 | 52.34 | 277 | 53.89 | 56 | 35.00 | 467 | 50.22 |
| missing | 0 | 0 | 4 | 4 | ||||
| Prior chemotherapy | ||||||||
| none | 126 | 49.22 | 325 | 63.98 | 96 | 58.54 | 547 | 58.94 |
| non-anthracycline | 130 | 50.78 | 162 | 31.89 | 34 | 20.73 | 326 | 35.13 |
| anthracycline | 0 | 0 | 21 | 4.13 | 34 | 20.73 | 55 | 5.93 |
| missing | 0 | 6 | 0 | 6 | ||||
| Prior endocrine therapy | ||||||||
| yes | 99 | 38.67 | 220 | 44.62 | 85 | 51.83 | 404 | 44.25 |
| missing | 0 | 21 | 0 | 21 | ||||
| Metastatic site | ||||||||
| high-risk* | 207 | 80.86 | 318 | 64.50 | 113 | 68.90 | 638 | 69.88 |
| missing | 0 | 21 | 0 | 21 | ||||