Table 3.
Overview of patient quality of life (QoL)
| Pre-Treatment | 1 Month | 3 Month | 6 Month | 9 Month | 12 Month | |
|---|---|---|---|---|---|---|
| SF-12 PCS | 50 (35.2 - 58.9) | 50.9 (31.4 - 61.4) | 50.5 (31.4 - 61.2) | 50.6 (25.7 - 56.7) | 49 (27.1 - 57.2) | 49 (27.6 - 59.8) |
| SF-12 MCS | 54.8 (37.2 - 61.3) | 54.4 (41.2 - 61) | 55.2 (37.3 - 63.2) | 55.7 (34.5 - 61.5) | 57 (47.1 - 64.7) | 56.5 (38.5 - 62.6) |
| AUA | 6.8 (1 - 21) | 10.8 (3 - 20) | 8.1 (1 - 21) | 7.7 (1 - 23) | 7.5 (2 - 26) | 7.4 (0 - 22) |
| SHIM | 17.2 (3 - 25) | 16 (1 - 25) | 15 (1 - 25) | 15.2 (1 - 25) | 15.6 (1 - 25) | 14.3 (1 - 25) |
| EPIC Urinary | 90.5 (63 - 100) | 82.7 (61.1 - 100) | 87.7 (53.7 - 100) | 88.5 (65.8 - 100) | 88.1 (68.6 - 100) | 89 (60.2 - 100) |
| EPIC Bowel | 95.7 (66.7 - 100) | 91.7 (62.5 - 100) | 92.6 (66.7 - 100) | 94.1 (70.8 - 100) | 94.1 (62.5 - 100) | 94.8 (75 - 100) |
| EPIC Sexual | 66.7 (27.8 - 95.8) | 66.4 (20.8 - 100) | 59.9 (0 - 100) | 59.8 (0 - 100) | 60 (16.7 - 100) | 60.1 (13.8 - 100) |
| EPIC Hormonal | 94.2 (75 - 100) | 90.9 (70 - 100) | 90.8 (60 - 100) | 92.3 (60 - 100) | 93.6 (60 - 100) | 92.1 (60 - 100) |
The table shows unadjusted changes in mean toxicity and QOL scores over time. SF-12 scores range from 0 - 100 with higher values representing improved health status. AUA scores range from 0 - 35 with higher values representing worsening urinary symptoms. SHIM scores range from 0 - 25 with lower values representing worsening sexual function. EPIC scores range from 0 - 100 with higher values representing a more favorable health-related QOL. Bolded items signify a statistically significant change in reported QoL from baseline measured by Wilcoxon rank sum test at 0.05 significance level.