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. 2011 Apr 27;6(4):e18381. doi: 10.1371/journal.pone.0018381

Figure 4. 3D homology models of the nematode proteins and the host orthologs for the PPI partners Q03601/Q20329.

Figure 4

A. B. malayi and H. sapiens homology models of Q03601; B. B. malayi and H. sapiens homology models of Q20329; and C. M. hapla and A. thaliana homology models of Q20329. All models are colored by electrostatic potential in vacuum. Q03601 did not have any protein sequences in A. thaliana with homology to M. hapla and M. incognita. Although regions of these proteins have homology to H. sapiens (A and B) and A. thaliana (C), the charges on the surface of H. sapiens and A. thaliana proteins are different from the charges on the surface of the nematode proteins. Further, Markov clustering did not group the H. sapiens or A. thaliana proteins in the same orthologous groups as the nematode proteins.