Table 1.
Demographic characteristics of renal allograft donors and recipients
Variable | Number of APOL1 G1-G2 nephropathy risk variants from kidney donor | ||
---|---|---|---|
Two | Zero or One | P-value | |
N=22 | N=114 | ||
Donor age (years) | 43.7 ± 16.8 | 47.7 ± 15.8 | 0.27 |
Donor gender (% male) | 66.3 | 60.0 | 0.26 |
Terminal serum creatinine (mg/dl) | 1.34 ± 0.8 | 1.19 ± 0.7 | 0.51 |
PRA* at transplant (%) | 13.4 ± 27.6 | 19.7 ± 31.3 | 0.48 |
PRA * > 0 (%) | 31.6 | 38.7 | 0.56 |
Donor African ancestry (%) | 0.77 ± 0.10 | 0.72 ± 0.21 | 0.53 |
Cold ischemia time (hours) | 22.5 ± 7.9 | 23.2 ± 8.0 | 0.82 |
HLA mismatch (N) | 4.2 ± 1.4 | 3.8 ± 1.5 | 0.29 |
Recipient gender (% male) | 77.3 | 53.5 | 0.04 |
Recipient age (years) | 45.2 ± 16.9 | 47.1 ± 16.2 | 0.72 |
Standard criteria donor (%) | 81.8 | 79.8 | 0.83 |
Recipient race (% African American) | 50.0 | 50.9 | 0.94 |
Diabetic ESRD in recipients (%) | 27.3 | 39.5 | 0.28 |
PRA - panel reactive antibody percentage