Table 2. Prevalence of CAG-expansion on haplogroup C.
| Avg overall HD prevalence per 100 000 | Haplogroup | Fraction of total | Prevalence of HD on haplogroup C | |
|---|---|---|---|---|
| Europe | 7.5 | C | 0.02 | 0.15 |
| All non-C | 0.98 | |||
| East Asia | 0.25 | C | 0.77 | 0.19 |
| All non-C | 0.23 |
Abbreviation: HD, Huntington disease.
The prevalence of HD on haplogroup C is similar between East Asia and Europe. HD is far more prevalent in Europe (7.5/100 000), but a small fraction of the total number of CAG-expanded chromosomes occur on haplogroup C (2%). Despite the lower overall prevalence of HD, the prevalence of CAG expansion specifically on haplogroup C is similar in the East Asian populations.