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. 2011 Jan 19;19(5):561–566. doi: 10.1038/ejhg.2010.229

Table 2. Prevalence of CAG-expansion on haplogroup C.

  Avg overall HD prevalence per 100 000 Haplogroup Fraction of total Prevalence of HD on haplogroup C
Europe 7.5 C 0.02 0.15
    All non-C 0.98  
East Asia 0.25 C 0.77 0.19
    All non-C 0.23  

Abbreviation: HD, Huntington disease.

The prevalence of HD on haplogroup C is similar between East Asia and Europe. HD is far more prevalent in Europe (7.5/100 000), but a small fraction of the total number of CAG-expanded chromosomes occur on haplogroup C (2%). Despite the lower overall prevalence of HD, the prevalence of CAG expansion specifically on haplogroup C is similar in the East Asian populations.