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. 2011 Jan 26;19(5):500–506. doi: 10.1038/ejhg.2010.241

Table 2. Preventive strategies adopted by BRCA1/2 carriers and non-carriers (all unaffected) 5 years after test result disclosure (N=246).

  Carriers (N=101) Non-carriers (N=145)
  Age category Age category
  Total <30 n=6 30–39 n=38 40–49 n=36 ≥50 n=21 Total <30 n=10 30–39 n=32 40–49 n=44 50 n=59
Preventive strategies n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Bilateral prophylactic mastectomy after test result delivery 7 (6.9) 0 2 (5.3) 4 (11.1) 1 (4.8) 0 0 0 0 0
Bilateral prophylactic oophorectomy 43 (42.6) 0 7 (18.4) 20 (55.6) 16 (76.2) 17 (11.7) 0 0 3 (6.8) 14 (23.7)
Before test result delivery 2   1 1 0 14     1 13
After test result delivery 41   6 19 16 3     2 1
                     
  m (SD)a m (SD)a m (SD)a m (SD)a m (SD)a m (SD)a m (SD) m (SD) m (SD) m (SD)
Mammograms during the previous 3 yearsb 2.8 (1.4) 1.8 (2.3) 2.6 (1.4) 3.1 (1.4) 3.2 (1.1) 1.7 (1.2) 0.5 (1.3) 0.9 (1.0) 1.7 (1.1) 2.2 (1.1)
MRI during the previous 3 yearsb 1.7 (1.7) 1.5 (2.1) 1.5 (1.5) 2.2 (2.0) 1.2 (1.4) 0.1 (0.4) 0.2 (0.7) 0.0 (0.2) 0.1 (0.5) 0.1 (0.3)
Ovarian ultrasoundc                    
Transvaginal US 1.7 (1.7) 0.5 (1.2) 1.4 (1.7) 2.3 (1.6) 2.6 (2.3) 0.7 (1.4) 0.6 (1.9) 1.0 (1.6) 0.5 (1.3) 0.6 (1.1)
Abdominal US 0.6 (1.2) 0.7 (1.2) 0.8 (1.5) 0.2 (0.8) 0 (0) 0.4 (1.2) 0.1 (0.3) 0.2 (0.8) 0.8 (1.8) 0.3 (0.8)
a

Mean number of investigations undergone during the last 3 years (means and SD).

b

Apart from RRM.

c

Apart from RRSO.