Table 4. Example table: net reclassification improvement based on addition of gene count score to Framingham offspring risk score.
Framingham offspring risk score plus gene count score | Reclassified | ||||||
---|---|---|---|---|---|---|---|
Framingham offspring risk score | <5% | 5–10% | 10–15% | >15% | Increased risk | Decreased risk | Net correctly reclassified |
People without diabetes during follow-up | |||||||
<5% | 2295 | 48 | 0 | 0 | |||
5–10% | 36 | 482 | 43 | 0 | 121 | 64 | −1.7% |
10–15% | 0 | 19 | 181 | 30 | |||
>15% | 0 | 0 | 9 | 181 | |||
People with diabetes during follow-up | |||||||
<5% | 52 | 8 | 0 | 0 | |||
5–10% | 2 | 37 | 3 | 0 | 14 | 11 | 1.5% |
10–15% | 0 | 4 | 24 | 3 | |||
>15% | 0 | 0 | 5 | 64 | |||
Net reclassification improvement −0.2% (95% CI −5.1 to +4.7); P=0.94. |
Adapted from ref. 52.