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. 2011 Mar 16;19(5). doi: 10.1038/ejhg.2011.27

Table 6. Example table: descriptive associations between demographic, environmental and genetic variables and progression to advanced age-related macular degeneration.

  Progressors, n (%) Non-progressors, n (%) OR (95% CI) P
Total patients 279 1167    
Age (years)
 <70 137 (49) 743 (64) 1.0  
 70+ 142 (51) 424 (36) 1.8 (1.4–2.4) <0.001
         
Sex
 Female 163 (58) 694 (59) 1.0 0.74
 Male 116 (42) 473 (41) 1.0 (0.8–1.4)  
         
Education
 ≤High school 119 (43) 383 (33) 1.0 0.002
 >High school 160 (57) 784 (67) 0.7 (0.5–0.9)  
         
Baseline AMD grades
 2 8 (3) 446 (38) 1.0  
 3 161 (58) 566 (48) 15.9 (7.7–32.6) <0.001
 4 110 (39) 155 (13) 39.6 (18.9–83.0)  
         
Smoking
 Never 110 (39) 557 (48) 1.0  
 Past 137 (49) 564 (48) 1.2 (0.9–1.6) 0.14
 Current 32 (11) 46 (4) 3.5 (2.1–5.8) <0.001
         
BMI
 <25 69 (25) 416 (36) 1.0  
 25–29 130 (47) 484 (41) 1.6 (1.2–2.2) 0.003
 30+ 80 (29) 267 (23) 1.8 (1.3–2.6) 0.001
         
Treatment group
 Placebo 74 (27) 264 (23) 1.0  
 Antioxidants 77 (28) 295 (25) 0.9 (0.7–1.3) 0.70
 Zinc 67 (24) 294 (25) 0.8 (0.6–1.2) 0.27
 Antioxidants and zinc 61 (22) 314 (27) 0.7 (0.5–1.0) 0.056
         
rs1061170
 TT 39 (14) 366 (31) 1.0  
 CT 116 (42) 521 (45) 2.1 (1.4–3.1)  
 CC 124 (44) 280 (24) 4.1 (2.8–6.1) <0.001
         
rs10490924
 GG 67 (24) 612 (52) 1.0  
 GT 138 (49) 446 (38) 2.8 (2.1–3.9) <0.001
 TT 74 (27) 109 (9) 6.2 (4.2–9.1)  
         
rs1410996
 TT 8 (3) 158 (14) 1.0  
 CT 74 (27) 472 (40) 3.1 (1.5–6.6) <0.001
 CC 197 (71) 537 (46) 7.2 (3.5–15.0)  
         
rs9332739
 GG 271 (97) 1075 (92) 1.0  
 CG/CC 8 (3) 92 (8) 0.3 (0.2–0.7) 0.005
         
rs641153
 CC 256 (92) 1023 (88) 1.0  
 CT/TT 23 (8) 143 (12) 0.6 (0.4–1.0) 0.06
         
rs2230199
 CC 124 (44) 652 (56) 1.0  
 CG 130 (47) 456 (39) 1.5 (1.1–2.0)  
 GG 25 (9) 59 (5) 2.2 (1.3–3.7) <0.001

Adapted from ref. 6.