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. 2011 Apr 21;4:5. doi: 10.3389/fneng.2011.00005

Figure 3.

Figure 3

Spatial stimulus selectivity of sMEA vs. tungsten microelectrode. The magnitude of evoked compound action potentials (CAPs; μV × ms) on the central–dorsal column surface was measured and then plotted over lateral distance from site of maximal CAP response (i.e., the longitudinal location of the stimulating electrodes; n = 13). CAP response magnitudes were calculated using the rectified, integrated, and baseline-subtracted responses for a fixed time window following the stimulus artifact. These values were then averaged over 10 trials for a given recording site on the dorsal column. Standard error bars are shown. (A) Comparison of CAP magnitude over lateral distance from site of maximal activation with sMEA (top) and tungsten electrodes (bottom) at multiple stimulus intensities. (B) Magnitude-normalized comparison of lateral spread of axonal tract activation for sMEA and tungsten electrodes. The magnitudes of evoked CAPs for the MEA electrode pair and the rigid electrode each decreased to below 50% within approximately 100 μm of either side of the site of maximal activation.