Table 2.
Lifetime health and economic outcomes of dengue vaccination per 1,000 vaccinated*
| Vaccine efficacy | Number of averted dengue episodes† | Cost per averted dengue case‡ USD (THB) | Number of averted DHF/DSS episodes† | Cost per averted DHF/DSS case‡ USD (THB) |
|---|---|---|---|---|
| Vaccination cost $1.50 | ||||
| 50% | 423 | 3.23 (101) | 39 | 34.87 (1,087) |
| 75% | 658 | −0.23 (−7) | 66 | −2.29 (−71) |
| 85% | 756 | −1.02 (−32) | 78 | −9.89 (−308) |
| 95% | 855 | −1.74 (−54) | 91 | −16.42 (−512) |
| Vaccination cost $15 | ||||
| 50% | 422 | 35.25 (1,099) | 39 | 380.81 (11,867) |
| 75% | 659 | 20.27 (632) | 66 | 203.78 (6,350) |
| 85% | 758 | 16.79 (523) | 77 | 164.32 (5,121) |
| 95% | 856 | 14.03 (437) | 91 | 131.57 (4,100) |
| Vaccination cost $30 | ||||
| 50% | 422 | 70.86 (2,208) | 39 | 757.74 (23,614) |
| 75% | 657 | 43.15 (1,345) | 65 | 433.14 (13,498) |
| 85% | 755 | 36.68 (1,143) | 78 | 357.43 (11,139) |
| 95% | 854 | 31.56 (984) | 91 | 295.07 (9,195) |
| Vaccination cost $60 | ||||
| 50% | 423 | 141.62 (4,413) | 39 | 1,526.70 (47,577) |
| 75% | 658 | 88.74 (2,765) | 65 | 891.26 (27,775) |
| 85% | 746 | 76.32 (2,378) | 78 | 742.69 (23,145) |
| 95% | 855 | 66.67 (2,078) | 91 | 626.55 (608,471) |
| Vaccination cost $100 | ||||
| 50% | 422 | 236.54 (7,371) | 39 | 2,545.94 (79,340) |
| 75% | 657 | 149.69 (4,665) | 65 | 1,509.62 (47,045) |
| 85% | 757 | 129.11 (4,023) | 78 | 1,256.01 (39,141) |
| 95% | 854 | 91.36 (2,847) | 91 | 1,061.80 (33,089) |
| Vaccination cost $200 | ||||
| 50% | 422 | 473.92 (14,769) | 39 | 5,113.14 (159,342) |
| 75% | 659 | 300.90 (9,377) | 66 | 3,015.89 (93,985) |
| 85% | 756 | 261.36 (8,145) | 78 | 2,545.34 (79,321) |
| 95% | 854 | 230.58 (7,186) | 91 | 2,159.17 (67,287) |
| Vaccination cost $300 | ||||
| 50% | 423 | 709.13 (22,099) | 39 | 7,628.91 (237,741) |
| 75% | 659 | 452.65 (14,106) | 66 | 4,521.93 (140,918) |
| 85% | 756 | 393.93 (12,276) | 78 | 3,813.18 (118,831) |
| 95% | 855 | 347.53 (10,830) | 91 | 3,265.71 (101,770) |
| Vaccination cost $400 | ||||
| 50% | 423 | 945.24 (29,457) | 39 | 10,145.75 (316,174) |
| 75% | 658 | 605.57 (18,871) | 66 | 6,028.47 (187,866) |
| 85% | 757 | 525.52 (16,377) | 78 | 5,088.88 (158,586) |
| 95% | 853 | 465.15 (14,496) | 91 | 4,377.52 (136,418) |
| Vaccination cost $500 | ||||
| 50% | 422 | 1,183.99 (36,897) | 39 | 12,688.70 (395,421) |
| 75% | 658 | 756.97 (23,590) | 66 | 7,556.47 (235,484) |
| 85% | 755 | 659.49 (20,552) | 77 | 6,438.22 (200,636) |
| 95% | 855 | 581.44 (18,120) | 91 | 5,445.09 (169,686) |
| Vaccination cost $600 | ||||
| 50% | 423 | 1,417.97 (44,188) | 39 | 15,326.05 (477,609) |
| 75% | 659 | 907.82 (28,291) | 65 | 9,163.16 (285,553) |
| 85% | 757 | 790.01 (24,619) | 78 | 7,646.04 (238,275) |
| 95% | 856 | 697.72 (21,743) | 91 | 6,530.53 (203,512) |
| Vaccination cost $700 | ||||
| 50% | 422 | 1,657.67 (51,658) | 39 | 17,783.49 (554,190) |
| 75% | 659 | 1,059.05 (33,003) | 66 | 10,574.00 (329,520) |
| 85% | 756 | 922.85 (28,759) | 78 | 8,977.13 (279,756) |
| 95% | 854 | 815.86 (25,425) | 91 | 7,689.85 (239,640) |
| Vaccination cost $800 | ||||
| 50% | 422 | 1,894.55 (59,040) | 39 | 20,291.23 (632,340) |
| 75% | 658 | 1,213.99 (37,832) | 65 | 12,230.44 (381,140) |
| 85% | 756 | 1,055.81 (32,902) | 78 | 10,198.75 (317,826) |
| 95% | 855 | 932.68 (29,065) | 91 | 8805.56 (274,409) |
*
USD = United States dollar; THB = Thai Baht; DHF = dengue hemorrhagic fever; DSS = dengue shock syndrome.
†
Per 1,000 individuals vaccinated.
‡
Negative cost values indicate cost savings.