Table 2.
Antibody prevalence and density in relation to parasite carriage by microscopy*
| CSP | Titer, median (IQR) | AMA-1 | Titer, median (IQR) | MSP-119 | Titer, median (IQR) | ||
|---|---|---|---|---|---|---|---|
| Prevalence, % (n/N) | Prevalence, % (n/N) | Prevalence, % (n/N) | |||||
| 1–5 years | Parasite-negative | 2.5 (2/79) | 31.1 (13.2–52.4)† | 25.0 (20/80)‡ | 194.5 (66.2–766.9)‡ | 19.2 (15/78) | 42.6 (11.4–119.5) |
| Parasite carrier | 7.8 (8/103) | 37.9 (21.4–61.5)† | 44.7 (46/103)‡ | 552.7 (167.9–1,429.3)‡ | 29.0 (29/100) | 63.9 (16.8–195.2) | |
| 5–14 years | Parasite-negative | 22.7 (20/88) | 71.2 (45.4–111.8) | 78.3 (72/92) | 1,215.9 (800.0–1,719.8) | 31.5 (29/92) | 55.3 (23.4–202.7) |
| Parasite carrier | 21.4 (25/117) | 60.5 (28.9–97.4) | 78.2 (93/119) | 1,391.3 (880.7–1,804.1) | 27.1 (32/118) | 64.0 (25.5–167.1) | |
| ≥ 15 years | Parasite-negative | 36.4 (112/308) | 93.0 (51.3–147.2) | 67.7 (216/319) | 1,063.6 (608.1–1561.2) | 62.3 (198/318) | 248.2 (94.1–478.8) |
| Parasite carrier | 34.7 (25/72) | 79.6 (49.3–152.9) | 76.3 (58/76) | 1,297.7 (769.6–1686.6) | 56.2 (41/73) | 190.5 (70.3–427.9) |
*
Median titer includes all individuals, also seronegatives. The prevalence or (log10-adjusted) titer were compared between parasite-positive and parasite-negative individuals by microscopy; these analyses were done for different age categories and adjusting for age within that category.
†
P = 0.05.
‡
P < 0.01.