Table 1.
No. (%) of cells |
|||
---|---|---|---|
All amacrine types | Ath5 + lineage | Ath5 + with Ptf1a | |
Narrow-field amacrine cell type | |||
Smooth 1 | 7 (5.0%) | 5 (4.0%) | 5 (3.6%) |
Smooth 2 | 13 (9.2%) | 0 (0%)*a | 2 (1.4%)*a |
Smooth OFF | 11 (7.8%) | 8 (6.5%) | 13 (9.4%) |
Smooth ON/OFF | 11 (7.8%) | 6 (4.8%) | 19 (13.8%) |
Varicose 1 | 8 (5.7%) | 18 (14.5%)*b | 7 (5.1%) |
Varicose 2 | 9 (6.4%) | 10 (8.1%) | 3 (2.2%)*a |
Varicose 3 | 8 (5.7%) | 3 (2.4%)a | 1 (0.7%)*a |
Varicose 4 | 4 (2.8%) | 1 (0.8%)a | 1 (0.7%)a |
Varicose OFF | 11 (7.8%) | 23 (18.5%)*b | 17 (12.3%) |
Varicose ON/OFF | 6 (4.3%) | 7 (5.6%) | 13 (9.4%)*b |
Varicose spidery OFF | 7 (5.0%) | 5 (4.0%) | 6 (4.3%) |
Varicose spidery ON/OFF | 8 (5.7%) | 6 (4.8%) | 7 (5.1%) |
Total narrow-field cells | 103 | 92 | 94 |
Medium-field amacrine cell type | |||
Smooth 1 | 2 (1.4%) | 2 (1.6%) | 0 (0.0%)a |
Smooth 3/4 | 4 (2.8%) | 1 (0.8%)a | 3 (2.2%) |
Varicose 1 | 4 (2.8%) | 6 (4.8%) | 5 (3.6%) |
Varicose OFF | 2 (1.4%) | 6 (4.8%)b | 5 (3.6%)b |
Varicose ON | 2 (1.4%) | 2 (1.6%) | 5 (3.6%)b |
Total medium-field cells | 14 | 17 | 18 |
Wide-field amacrine cell type | |||
Smooth 2 | 3 (2.1%) | 2 (1.6%) | 7 (5.1%)b |
Smooth 3/4 | 2 (1.4%) | 4 (3.2%)b | 2 (1.4%) |
Smooth OFF | 2 (1.4%) | 4 (3.2%)b | 2 (1.4%)b |
Varicose 2 | 4 (2.8%) | 1 (0.8%)a | 1 (0.7%)a |
Varicose 3 | 3 (2.1%) | 0 (0%)a | 7 (5.1%)b |
Varicose OFF | 5 (3.5%) | 2 (1.6%)a | 2 (1.4%)a |
Varicose ON | 3 (2.1%) | 0 (0.0%)a | 3 (2.2%) |
Varicose ON/OFF bistratified | 2 (1.4%) | 2 (1.6%) | 2 (1.4%) |
Total wide-field cells | 24 | 15 | 26 |
Total inner nuclear layer amacrine cells | 141 | 124 | 138 |
Number and percentage of each subtype is shown. WT data are from the study by Jusuf and Harris (2009). No., Number. Statistically significant at *p < 0.005.
aSubtypes that are underrepresented by at least a factor of two. Bold represents the five subtypes that are underrepresented in both lineages.
bSubtypes that are overrepresented by at least a factor of two.