Table 1.

Pharmacological profile of oral PDE5-i at therapeutic dosage for ED

Parameter	Sildenafil 100 mg	Tadalafil 20 mg	Vardenafil 20 mg
Tmax (h)	1.16 ± 0.99	2	0.66 (0.250-3.0)
T1/2 (h)	3.82 ± 0.84	17.5	3.94 ± 1.31
C (max ng/m)	327 ± 236	378	20.9 ± 1.83
AUC (ng × h/m)	1963 ± 859	8066	74.5 ± 1.82

PDE5-i: Phosphodiesterase type-5 inhibitor; ED: Erectile dysfunction.