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. 2011 Apr 4;2:19. doi: 10.3389/fneur.2011.00019

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Copyright © 2011 Pun, Kan, Salim, Li, Ng, Moochhala, Ling, Tan and Lu.

This is an open-access article subject to a nonexclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.

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Clustering of probe sets with significant time-course evolution. A total of 203 probe sets showing such evolution were identified, and grouped into eight clusters based on their time-evolution profiles. Probe sets in cluster 1 showed no major variation over time. They are consistently and weakly up-regulated or down-regulated across all time-points. Those in clusters 2 and 6 were up-regulated while those in clusters 3 and 7 were down-regulated at day 4. Probe sets in clusters 4, 5, and 8 were respectively down-regulated at day 7, up-regulated at day 1 and day 4, and up-regulated at day 1 only.