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. 2010 Aug 26;1(8):254–264. doi: 10.4331/wjbc.v1.i8.254

Figure 3.

Figure 3

MICAL-L1 and MICAL-L2 regulate endocytic recycling. A: MICAL-L1 recruits Eps15 homology domain 1 (EHD1) and Rab8A to endocytic membranes and regulates recycling of transferrin and β1 integrin receptors; B: MICAL-L2/Rab13 interactions control transport of claudin-1 and occludin to the plasma membrane, whereas MICAL-L2/Rab8 complexes regulate recycling of E-cadherin. EE/SE: Early endosome/sorting endosome; RE: Recycling endosome; AEE: Apical early endosome; CRE: Common recycling endosome; ARE: Apical recycling endosome.