Figure 4.
Schematic representation of binding region and catalytic site of a protease. This hypothetical protease possesses six subsites (S1-S3 and S1’-S3’) in its catalytic site and, consequently, is able to recognize and bind to a sequence of six amino acids (P1-P3 and P1’-P3’) in the proteinaceous substrate. After proteolysis, at least two smaller peptides are generated as the reaction products.