Table A4.

EGFR Quartiles by Patient and Disease Characteristics

Characteristic	EGFR Quartiles								All
	Q1		Q2		Q3		Q4
	No.	%	No.	%	No.	%	No.	%	No.	%
Treatment
Standard	38	50.7	44	58.7	30	40.0	42	56.0	154	51.3
Accelerated fractionation with concomitant boost	37	49.3	31	41.3	45	60.0	33	44.0	146	48.7
Sex
Male	52	69.3	58	77.3	61	81.3	55	73.3	226	75.3
Female	23	30.7	17	22.7	14	18.7	20	26.7	74	24.7
KPS
60	4	5.3	3	4.0	5	6.7	2	2.7	14	4.7
70	4	5.3	10	13.3	11	14.7	14	18.7	39	13.0
80	17	22.7	16	21.3	18	24.0	18	24.0	69	23.0
90	41	54.7	35	46.7	26	34.7	30	40.0	132	44.0
100	9	12.0	11	14.7	15	20.0	11	14.7	46	15.3
Age, years
≤ 55	19	25.3	21	28.0	28	37.3	21	28.0	89	29.7
56-65	32	42.7	24	32.0	27	36.0	37	49.3	120	40.0
≥ 66	24	32.0	30	40.0	20	26.7	17	22.7	91	30.3
Primary site
Oral cavity	4	5.3	7	9.3	14	18.7	10	13.3	35	11.7
Oropharynx	47	62.7	40	53.3	39	52.0	40	53.3	166	55.3
Hypopharynx	11	14.7	9	12.0	8	10.7	13	17.3	41	13.7
Larynx	13	17.3	19	25.3	14	18.7	12	16.0	58	19.3
T stage
T1	9	12.0	9	12.0	2	2.7	3	4.0	23	7.7
T2	27	36.0	22	29.3	17	22.7	13	17.3	79	26.3
T3	21	28.0	26	34.7	29	38.7	33	44.0	109	36.3
T4	18	24.0	18	24.0	26	34.7	26	34.7	88	29.3
Tx	—	—	—	—	1	1.3	—	—	1	0.3
N stage
N0	12	16.0	15	20.0	15	20.0	15	20.0	57	19.0
N1	9	12.0	15	20.0	15	20.0	20	26.7	59	19.7
N2a	10	13.3	7	9.3	9	12.0	5	6.7	31	10.3
N2b	19	25.3	12	16.0	15	20.0	12	16.0	58	19.3
N2c	16	21.3	16	21.3	13	17.3	14	18.7	59	19.7
N3	9	12.0	10	13.3	8	10.7	9	12.0	36	12.0

Abbreviations: EGFR, epidermal growth factor receptor; Q, quartile; KPS, Karnofsky performance score.