Table 1. Baseline parameter values for latent cell activation model.
Parameter | Description | Estimate |
Death rate of latently infected cells | ||
Virion production rate for a productively infected cell | 5000, 10000, 20000 | |
Death rate of productively infected cells | ||
Clearance rate of free virions | ||
Mass-action infectivity of free virions | ||
Target cells | ||
Drug efficacy | 0.93 | |
Fraction of new infections that result in latency | 0 | |
Half life of latent reservoir | 60 months | |
Initial number of latently infected cells | 1 per target cells |