Figure 2.

Quantitation of EMT and cell proliferation. Quantitation of a-SMA positive area (A) and BrdU-positive cells (B) in control (blue) and C5aR antagonist-treated animals (red). These graphs were made from sections received in the experiment described in Figure 1. Panel A confirms that C5aR antagonist caused delay of EMT but also affected proliferation of lens epithelial cells as well. The asterisks indicate the time when the results are statistically significant, p=0.042<0.05 for α-SMA and p=0.02<0.05 for BrdU/Hoechst.