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. 2011 Apr 28;6(4):e19146. doi: 10.1371/journal.pone.0019146

Table 1. Characteristics of the study cohort by genotype for three SNPs of FFAR1.

rs2301151 rs1573611 rs16970264
SNP Type/location Non-synonymous Near gene 3′ Near gene 5′
AA AG GG P CC TC TT P AA GA GG P
n 233 156 16 247 138 20 3 47 350
Genotype frequency 0.58 0.38 0.04 0.61 0.34 0.05 0.01 0.12 0.87
Minor allele F 0.23 0.22 0.07
Age 52.4 (9.6) 54.4 (10.3) 52.4 (11.2) 0.16 53.6 (10.2) 52.6 (9.5) 54.4 (10.4) 0.56 56.7 (5.13) 54.4 (8.9) 53.0 (10.1) 0.56
Gender (M%/F%) 43/57 42/58 19/81 0.16 40/60 44/56 50/50 0.89 67/33 40/60 41/59 0.91
MS score 6 [5,7] 6 [5,8] 6 [5,8] 0.26 6 [5,8] 6 [5,8] 6 [4,6.5] 0.42 7 [6,8] 7 [5,8] 6 [5,7] 0.09
CVD score 2 [1,4] 2 [1,5] 1 [1,3] 0.35 2 [1,5] 2 [1,4] 4 [1,7] 0.43 2 [1,9] 2 [1,5] 2 [1,4] 0.83

The data are presented as mean (SD) for age, proportion (%) for gender and median [IQR] for metabolic syndrome (MS) and cardiovascular disease (CVD) risk score for each genotype of the three SNPs of FFAR1 which were investigated. Differences (P) in characteristics between genotypes are indicated. The MS and CVD risk score were study specific see Jebb et al. [9]. SNP location data from the NCBI-SNP database.