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. 2011 Apr 28;6(4):e19146. doi: 10.1371/journal.pone.0019146

Table 2. BMI, waist circumference and body fat by genotype for three SNPs of FFAR1.

rs2301151 rs1573611 rs16970264
Difference P Difference P Difference P
AA AG GG TT TC CC AA AG GG
BMI (kg/m2)
mean 28.71 29.41 30.01 0.67 0.11 25.61 28.86 29.31 1.06 0.009 28.53 29.53 28.85 0.55 0.41
SE 0.32 0.35 1.67 0.85 0.41 0.31 2.25 0.60 0.26
n 233 156 16 20 138 247 3 47 350
Waist circumference (cm)
mean 98.60 98.57 98.09 0.27 0.79 93.53 98.89 98.53 1.29 0.19 100.23 100.57 97.95 2.09 0.20
SE 0.85 0.95 2.72 3.02 1.09 0.76 4.41 1.68 0.66
n 233 156 16 20 138 247 3 47 350
Body fat (%)
mean 33.19 34.77 37.34 1.11 0.03 28.05 33.30 34.68 1.53 0.002 28.50 35.02 33.88 −0.58 0.48
SE 0.56 0.69 1.99 1.52 0.71 0.55 3.70 1.31 0.46
n 228 155 16 20 136 244 3 47 345

Data are presented as mean, SEM, n stratified by genotype for each of the three SNPs. For each genotype the risk allele was defined as the BMI-increasing allele and the data are presented as the additive model. The differences in trait by genotype were assessed by linear regression analysis coding the number of risk alleles as 0,1,2. The P-value for the regression is presented and is in bold when reaching significance by the FDR-controlling procedure q* = 0.05. The recessive and dominant models defined according to the risk allele are shown in Supplementary Table S1.