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. 2011 Apr 28;6(4):e19218. doi: 10.1371/journal.pone.0019218

Table 2. Summary of all data generated by behavioral observations and the pup retrieval test.

Balb/c GR +/+ Balb/c GR +/− C57Bl/6N GR +/+ C57Bl/6N GR +/− Transf Strain Genotype Interaction
In nest
licking/grooming [%] 7,951±1,070 9,790±1,454 16,615±1,273 11,101±2,476 NT 0,008 ** 0,043 *
active nursing [%] 14,613±4,955 9,913±3,589 6,130±2,323 11,800±3,654 sqrt
passive nursing [%] 43,471±4,482 49,027±3,801 64,870±4,993 57,299±7,275 NT 0,013 *
nest building [%] 6,624±1,089 6,058±1,317 5,532±0,857 10,346±3,220 sqrt
self-grooming [%] 4,517±0,579 6,140±1,710 3,848±0,863 5,304±1,214 sqrt
pups out of nest [%] 5,507±2,484 2,070±1,485 1,498±1,265 0,246±0,123 sqrt 0,086 T
Out of nest
eating/drinking [%] 10,387±2,299 10,835±1,664 14,422±3,166 10,067±3,808 NT
self-grooming [%] 1,783±0,410 2,908±1,037 1,010±0,338 0,360±0,198 sqrt 0,002 **
climbing/digging [%] 6,924±1,514 5,578±1,186 1,718±1,254 2,477±1,123 NT 0,004 **
Pup retrieval test
handling [%] 26,410±4,661 24,658±5,226 34,614±8,825 47,402±6,456 NT 0,048 *
pups back in nest [s] 165,286±35,313 135,600±35,730 107,167±33,491 83,000±22,290 angular
crouching over pups [s] 232,714±33,622 166,600±39,829 178,500±41,680 206,143±44,680 angular 0,051 T

Data analysis was done using GLMs on the basis of 26 dams belonging to four different treatment groups: Balb/c wildtypes (+/+; n = 7), Balb/c with a heterozygous mutation of the GR (+/−; n = 6 for behavioral observations, n = 5 for the pup retrieval test) C57BL/6N wildtypes (+/+; n = 6), C57BL/6N with a heterozygous mutation of the GR (+/−; n = 7). Data are given as untransformed means ± standard error of the mean (s.e.m.). The statistical analysis is summarized with respect to the transformation used (NT = not transformed, sqrt = square root transformation, angular = angular transformation) and the effects of “strain”, “GR genotype” and “strain-by-GR-genotype-interaction” (T = tendency; *p<0.05, **p<0.01).