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. 2011 Apr 28;6(4):e19253. doi: 10.1371/journal.pone.0019253

Table 2. Dissociation constants of human ODC-AZ and AZI-AZ complexes.

[ODC-AZ] complex K d,ODC-AZ (µM) [AZI-AZ] complex K d,AZI-AZ (µM)
ODC_WT 0.21±0.001 AZI_WT 0.02±0.009
ODC_N125K 0.10±0.001 AZI_K125N 0.16±0.009
ODC_M140K 0.14±0.001 AZI_K140M 0.11±0.001
ODC_N125K/M140K 0.02±0.002 AZI_K125N/K140M 0.18±0.01

The dissociation constants (K d) of ODC-AZ and AZI-AZ were derived from the global fitting of the sedimentation velocity data to the model of A+B↔AB hetero-association in the SEDPHAT program.