Table 1.
Levels |
|||
---|---|---|---|
–1 | 0 | 1 | |
Independent variables | |||
X1 = Amount of lipid (w/v) | 5% | 7.5% | 10% |
X2 = Amount of surfactant (w/v) | 2% | 5% | 8% |
X3 = Drug/lipid ratio (w/w) | 5% | 10% | 15% |
Dependent variables | Constraints | ||
Y1 = Entrapment efficiency (EE%) | Maximize | ||
Y2 = Drug loading (DL%) | Maximize | ||
Y3 = Turbidity (NTU) | Minimize |