Table 3.

Observed and predicted value of encapsulation efficiency (Y₁), drug loading (Y₂) and turbidity (Y₃) of formulations in the Box-Behnken design

Formulation	Observed Y1	Predicted Y1	Observed Y2	Predicted Y2	Observed Y3	Predicted Y3
1	41.26	34.64	3.95	4.04	32	36.5
2	74.68	81.30	6.96	6.88	26	21.5
3	75	70.35	6.95	6.79	42	50
4	30.13	39.60	4.32	5.39	24	15.5
5	63.68	65.68	5.98	6.16	35	35.6
6	53.91	58.56	5.11	5.27	124	116
7	67.32	65.68	6.32	6.16	33	35.6
8	67.53	65.68	6.32	6.16	38	35.6
9	36.38	41.20	1.79	2.68	69	68.5
10	63.11	65.68	5.92	6.16	26	35.6
11	76.4	74.60	10.29	11.28	39	43
12	66.74	65.68	6.24	6.16	46	35.6
13	55.85	57.65	7.74	6.76	23	19
14	56.75	53.90	7.84	6.69	62	66
15	67.01	57.54	3.26	2.20	34	42.5
16	80.77	83.62	3.88	5.02	31	27
17	74.74	69.92	9.61	8.72	26	26.5