Figure 5.

Confocal laser scanning microscopic (CLSM) micrographs of nude mouse skin after the in vivo topical administration of 5-aminolevulinic acid (ALA) via the skin for 8 hours from the aqueous control (double-distilled water) (A), ALA from oil-in-water (O/W) soybean oil emulsions (W1) (B), methyl (m)ALA from the aqueous control (double-distilled water) (C), and mALA from O/W soybean oil emulsions (W1) (D). The skin specimen was viewed by CLSM at −10-μm increments by a separate X, Y-sections at each Z-axis from the skin surface to the bottom as the arrows indicate (left to right, top to bottom).