. Author manuscript; available in PMC: 2012 Apr 1.

Published in final edited form as: Obstet Gynecol. 2011 Apr;117(4):899–905. doi: 10.1097/AOG.0b013e3182110ea3

Table 2.

Hazard ratios (HR) for association between body mass index (BMI) at age 20 years and endometrial cancer risk for mismatch repair gene mutation carriers and noncarriers.

BMI per 5 kg/m²	Total number	Total person-years	Number (%) of endometrial cancer cases	Univariable Analysis^*		Multivariable Analysis^†

				HR (95% CI)	P	HR (95% CI)	P
Carriers	601	26,027	126 (21)	0.67 (0.38–1.20)	0.18	0.73 (0.40–1.34)	0.31
Non-carriers	533	25,666	8 (2)	1.58 (1.00–2.48)	0.05	1.74 (1.27–2.37)	<0.001

With robust variance correction for familial correlation in risk.

^†

Adjusted for age at menarche, year of birth, use of hormonal contraceptives, and cigarette smoking at age 20 in both carriers and noncarriers; further adjusted for specific mismatch repair gene mutated for carriers.