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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Lab Invest. 2011 Mar 7;91(5):665–674. doi: 10.1038/labinvest.2011.7

Figure 2.

Figure 2

Intimal plaque replacing >50% of an arterial lumen from an untreated MPS-I dog contains smooth muscle and/or myofibroblasts (brown stain) with some loss of normal muscle structure in the media (asterisk; α-smooth muscle actin IHC).