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. Author manuscript; available in PMC: 2012 Jun 11.
Published in final edited form as: Eur J Pharmacol. 2011 Jan 3;660(1):119–124. doi: 10.1016/j.ejphar.2010.10.105

Fig. 1.

Fig. 1

Organization and imprinting of the GNAS gene. The maternal and paternal alleles of the GNAS gene are depicted showing four alternative first exons for NESP55 (NESP), XLαs, 1A mRNA transcripts, and Gsα (exon 1) splicing onto common exons 2 through 13 (shown as a single box). Regions of differential methylation (METH) are shown above and splicing patterns are shown below each allele. Active promoters are shown in white with horizontal arrows while inactive promoters are shown in gray. The thin and dashed arrow for the paternal Gsα promoter indicates that this promoter is suppressed in a tissue-specific manner due to genomic imprinting.