Table 1.

Clinical and neuropathological characteristics of patients and controls

Patients	Sex	Age (y)	Ethnicity	PMI (h)	Parietal cortex atrophy	Neuritic plaques	Neuropil threads	Neuronal loss	Gliosis
Normal
#1	F	89	Caucasian	8.4	Moderate	None	None	None	None
#2	F	105	Caucasian	6.0	Mild	None	None	None	None
#3	M	81	Hispanic	3.0	Mild	None	None	None	None
#4	F	87	Caucasian	7.0	None	None	None	None	None
AD (Braak & Braak score IV - V)+ Amyloid angiopathy
#5	F	89	Caucasian	9.0	Mild	Moderate	Sparse	None	None
#6	F	87	Hispanic	6.0	Mild	Moderate	Sparse	None	Sparse
AD (Braak & Braak score V)
#7	M	83	Hispanic	7.0	Mild	Frequent	Moderate	None	None
#8	F	92	Caucasian	4.8	Mild	Moderate	Sparse	None	None
#9	F	99	Caucasian	7.5	Mild	Sparse	None	None	None
#10	M	76	African-American	5.0	Moderate	Frequent	Moderate	Sparse	Sparse
AD (Braak & Braak score VI)
#11	F	80	ND	11.0	Moderate	Moderate	Frequent	None	None
#12	M	91	ND	7.0	Moderate	Frequent	Frequent	None	None

Neuropil threads and senile (neuritic) plaques are reported for parietal cortex and refer to assessment by silver (Gallyas) stain or immunohistochemistry. The plaque number includes plaques with and without amyloid cores; sparse (<5/field), mod (6 to 20/field), freq (21 to 30/field).

Abbreviations: F, female; M, male; ND, not documented; PMI, post-mortem interval.