Table 1.

Sociodemographic characteristics, substance use characteristics, and detoxification treatment status of 79 problem drinking-opioid dependent (PD-OD) patients, 61 non-problem-drinking OD (AU-OD) patients, and 34 non-alcohol-using OD (N-AU-OD) patients undergoing 6-day metha-done detoxification

	PD-OD	AU-OD	N-AU-OD
	(n = 79)	(n = 61)	(n = 34)
Variable	% or M(SD)	% or M(SD)	% or M(SD)
Demographics
Age	32.2 (8.2)	29.8 (7.6)	33.9(5.1)
Male	67.1	68.8	64.7
African American	24.9	19.7	20.6
Years of education	10.3 (4.2)	9.8 (2.2)	9.8 (1.7)
Married or cohabitant	15.6	14.7	17.6
Unemployed	62.0	59.0	64.7
Substance use
Days of use in last month
Opioids	21.6(2.9)	19.9 (2.5)	22.1 (1.5)
Alcohol**	9.8 (2.5)	2.9 (2.8)	N.A.
Cocaine	6.5 (4.5)	6.9 (3.5)	7.2(1.5)
Cannabis	4.7 (6.6)	6.1 (4.1)	6.1 (4.1)
Years of use
Opioids	9.7 (2.7)	7.7 (3.7)	8.1 (1.7)
Alcohol	8.9 (4.8)	7.8 (3.9)	N.A.
Cocaine	5.6 (4.2)	6.6 (3.5)	4.6(3.1)
Cannabis	7.8 (2.6)	6.7 (3.2)	7.7(1.2)
Addiction Severity Index
Drug composite score	.27 (.16)	.28 (.17)	.21 (.17)
Alcohol composite score	.22 (.19)	N.A.	N.A.
Psychiatric composite score	.26 (.13)	.22 (.14)	.24 (.10)
Other drug tests at admission
Positive cocaine	41.8	44.3	41.2
Positive cannabis	38.0	40.1	44.1
Positive amphetamine	3.8	4.9	5.9
Opioid withdrawal scores at admission
SOWS (0–64)	34.2(11.8)	35.1 (12.1)	31.4(8.9)
OOWS (0–13)	4.4 (2.9)	4.8 (2.6)	3.9 (1.6)
Craving (0–3)	2.9(0.1)	2.7 (0.3)	2.4 (0.3)
Treatment randomization
Placebo	30.4	34.4	35.3
Naltrexone 0.125 mg/day	36.7	32.8	29.4
Naltrexone 0.250 mg/day	32.9	32.8	35.3

Notes: n.a. = not applicable; SOWS = Subjective Opiate Withdrawal Scale; OOWS = Objective Opiate Withdrawal Scale.

^**F(1, 140) = 3.1,p = .01. All other comparisons are nonsignificant.