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. Author manuscript; available in PMC: 2011 Apr 29.
Published in final edited form as: Nat Mater. 2010 Oct 24;9(12):1004–1009. doi: 10.1038/nmat2875

Figure 1. Cryo-electron tomography of a collagen fibril mineralized in the presence of 10 µg ml−1 of pAsp for 72 h and stained with uranyl acetate.

Figure 1

a, Two-dimensional cryoTEM image. b, Slice from a section of the three-dimensional volume along the xy plane (top-most inset), where crystals are visible edge-on (insets 1 and 2, white arrows). Black circle: ACP infiltrating the fibril (see below). c, Computer-generated three-dimensional visualization of mineralized collagen. The fibril is sectioned through the xy plane, revealing plate-shaped apatite crystals (coloured in pink) embedded in the collagen matrix. Scale bars: 100 nm.