. 2009 Jun 11;10(3):383–396. doi: 10.1007/s10162-009-0171-1

TABLE 2.

Mobility parameters in the three OHC regions after cholesterol manipulations

	Depleted	Control	Loaded
M_f (%)
Lateral	90 ± 6	94 ± 5^a	88 ± 5^a
Basal	80 ± 11	85 ± 9	84 ± 7
Apical	72 ± 12	76 ± 11	79 ± 4
D (μm²/s)
Lateral	1.08 ± 0.60	1.67 ± 0.89^a	0.81 ± 0.42^a
R²	0.84 ± 0.10	0.83 ± 0.09	0.87 ± 0.08
Basal	0.97 ± 0.36^b	1.29 ± 0.47	1.64 ± 0.54^b
R²	0.84 ± 0.08	0.81 ± 0.11	0.75 ± 0.08
Apical	3.22 ± 1.93	5.26 ± 3.95	3.71 ± 3.16
R²	0.60 ± 0.14	0.56 ± 0.17	0.58 ± 0.21

Only the lateral region showed significant changes in M_f after cholesterol treatments with loading decreased from control (p < 0.05). The effective diffusion coefficient, D, of the lateral region significantly decreased after cholesterol loading (p < 0.01). In the basal region, cholesterol loading and depletion resulted in D values that were statistically significant from one another (p < 0.01). No change was seen in the apical region D values following cholesterol manipulations (p > 0.3). Values shown are mean ± SD. In the lateral region, n was 10, 17, and 11 for depleted, control and loaded, respectively. In the basal region, n was 10, 13, and 11, and in the apical region, n was 10, 15, and 10. R² values demonstrating goodness of fit for calculations of D are also provided

^aSignificant differences from control

^bSignificant difference between loading and depletion