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. 2009 Apr 2;10(3):341–353. doi: 10.1007/s10162-009-0166-y

FIG. 10.

FIG. 10

Treatment with VPA does not affect hair cell differentiation during regeneration. Organotypic cultures of the chick utricle were treated for 24 h with 1 mM streptomycin, rinsed and maintained for 4 days in drug-free medium, and then treated for 4 days with 1 mM VPA. Cultures were fixed and HCS-1-labeled hair cells were quantified. Treatment with VPA caused no significant change in hair cell recovery (p > 0.10), suggesting that HDAC inhibition does not affect hair cell differentiation. Error bars: standard deviation.