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Effect of various inhibitors on 25 µM ciprofloxacin (A) B→A transport; (B) A→B transport and (C) B→A/A→B ratio in MDCK1-MDR1 cells. The inhibitors are GG918 (2.5 µM),cyclosporine (20 µM),ketoconazole (100 µM), vinblastine (100 µM), verapamil (50 µM), trimethoprim (100 µM), quinidine (100 µM), dicloxacillin (100 µM), erythromycin (100 µM), probenecid (100 µM), PAH (100 µM), glycosarcosine (10 mM), sulfinpyrazone (1 mM) and TEA (100 µM). *P < 0.01 **P < 0.05.
