Table 5.

The diffusion coefficients of hydrocortisone from eight formulations diffusing through pre-washed mouse skin

Formulation	n	Permeability coefficient(cm/hr)	R2
Corticool gel*	3	3.22 * 10−3	0.985
Cortizone-10 plus cream †	4	1.261 * 10−3	0.998
Cortaid cream †	5	2.425 * 10−3	0.964
Cortaid lotion †	3	1.851 * 10−3	0.998
Cortizone-10 ointment*	3	3.194 * 10−5	0.904
Aveeno cream †	6	2.479 * 103	0.998
Prescription HC 2.5% †	6	1.877 * 10−3	0.999

^*The diffusion coefficient with solubility 1 mg/mL.

^†The diffusion coefficient with solubility 0.28 mg/mL.