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. 2011 Apr 13;31(15):5730–5736. doi: 10.1523/JNEUROSCI.5668-10.2011

Table 3.

Effect of α-, β1-, or β3-adrenergic receptor antagonists on intestinal OEA levels (pmol/g)

α-Adrenergic antagonist
β1-Adrenergic antagonist
β3-Adrenergic antagonist
V Prazosin V CGP2071 V SR59230
FD 68.1 ± 7.4 55.4 ± 5.4 58.2 ± 8.3 67.1 ± 3.5 90.3 ± 9.5 114.2 ± 8.9
RF 172.1 ± 25 123.5 ± 21.7 155.5 ± 21.7 108 ± 9.4 186.5 ± 23.6 172.3 ± 23.8

Administration of α-, β1-, or β3-adrenergic receptor antagonists does not affect jejunal OEA levels in refed rats. Thirty minutes of refeeding (RF) after 24 h of food deprivation in vehicle (V)-treated animals increased jejunal OEA levels compared to 24 h food deprivation alone (FD). Systemic treatment with α- (prazosin), β1- (CGP2071), or β3- (SR59230A) adrenergic receptor antagonists did not alter OEA mobilization. Results are expressed as mean ± SEM; n = 6/condition.